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. 2024 Nov 22;19:12505–12527. doi: 10.2147/IJN.S474665

Table 1.

Physicochemical Characterization of Selected Hybrid Nanosystems and Their Components

Size (nm) Polydispersity Index (PDI) Zeta Potential (mV)
PLGA nanoparticles 92.3 ± 0.4 0.02 ± 0.01 21.5 ± 0.61
PLGA nanoparticles/DNA (1/8 ratio) 112.5 ± 2.3 0.20 ± 0.02 −31.2 ± 7.39
Liposomes without Galnac 97.9 ± 0.4 0.17 ± 0.05 25.3 ± 1.28
Liposomes with Galnac 102 ± 0.1 0.18 ± 0.03 −15.4 ± 2.01
Hybrid nanoparticles without Galnac 129 ± 0.8 0.08 ± 0.07 19.5 ± 0.78
Hybrid nanoparticles with GalNac 135 ± 0.5 0.07 ± 0.09 −17.6 ± 0.93

Notes: Results are presented as mean ± SD obtained at least from four independent samples.