Figure 9.

DCE-MRI image and histology image of Case 4. Higher K^trans (A), V_p (C), and k_ep (D) are found in the peripheral mass region (arrow) compared to the central mass region (asterisk) and adjacent normal muscle. The central mass region (asterisk) shows higher K^trans (A), V_e (B), V_p (C), and k_ep (D) compared to the adjacent normal muscle, and slightly higher V_e (B) compared to the peripheral mass region (arrow). TIC (E) in the central mass region shows a progressive pattern; TIC (F) in the peripheral mass region shows a rapid wash-in and slow wash-out pattern. A histopathological image (G), stained with hematoxylin and eosin (H&E) and observed at 400× magnification, shows lobules of varying sizes composed of squamous epithelial cells in the dermis. The histopathologic result indicates a diagnosis of SCC in situ based on the imaging findings and the patient’s clinical signs, the mass was ultimately concluded to be SCC by a veterinary radiologist, veterinary pathologist, and veterinary surgeon.