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Oogenic defects of PIWI mutants in hamsters. PIWIL1 deficiency results in arrest at the 2-cell stage. PIWIL2-KO mutants have no defects in oocytes. PIWIL3 deficient hamsters arrest at the 2-cell stage, but some fertilized oocytes complete development. Solid lines show normal development; red crosses (x) indicate the stage of developmental block.
