Table 1.
Physical characteristics, blood constituents, and glycemic control at baseline and changes after intervention
| Baseline | Changes after intervention | Two-way ANOVA [group x time]b | ||||
|---|---|---|---|---|---|---|
| CNT | HPR | CNT | HPR | P value | ||
| n | 24 | 25 | 24 | 25 | ||
| Sex (men: women) | 9: 15 | 8: 17 | 9: 15 | 8: 17 | ||
| Age, yr | 71 ± 5 | 69 ± 5 | NA | NA | – | |
| Height, cm | 159 ± 9 | 158 ± 8 | NA | NA | – | |
| Body weight, kg | 58.8 ± 2.1 | 58.8 ± 1.9 | 0.6 ± 0.3** | 0.4 ± 0.2** | 0.57 | |
| BMI, kg/m2 | 23.3 ± 0.7 | 23.6 ± 0.6 | 0.2 ± 0.1** | 0.2 ± 0.1** | 0.61 | |
| SBP, mmHg | 146 ± 4 | 147 ± 3 | 5 ± 2* | 3 ± 3 | 0.58 | |
| DBP, mmHg | 78 ± 2 | 83 ± 2 | 3 ± 1 | −1 ± 2 | 0.11 | |
| , ml/min | 1455 ± 75 | 1511 ± 73 | −11 ± 32 | 12 ± 32 | 0.61 | |
| HRpeak, beats/min | 146 ± 5 | 140 ± 3 | 3 ± 4 | 3 ± 3 | 0.99 | |
| LDL-C, mg/dl | 124 ± 6 | 123 ± 7 | 2 ± 5 | 3 ± 4 | 0.90 | |
| HDL-C, mg/dl | 73 ± 5 | 68 ± 4 | 0 ± 2 | 1 ± 1 | 0.49 | |
| TG, mg/dl | 113 ± 12 | 120 ± 13 | −10 ± 15 | −20 ± 10 | 0.56 | |
| [Glc]fast, mg/dl | 110 ± 3 | 112 ± 4 | 6 ± 2** | 2 ± 2 | 0.59 | |
| HbA1c, % | 6.0 ± 0.1 | 6.1 ± 0.1 | 0.1 ± 0.1 | 0.0 ± 0.0 | 0.41 | |
| Insulin, μU/ml | 6.7 ± 0.7 | 6.8 ± 0.8 | 1.1 ± 0.5** | 0.8 ± 0.4** | 0.67 | |
| CGM [Glc]a (average of days 2–5) | ||||||
|---|---|---|---|---|---|---|
| All day | ||||||
| Mean, mg/dl | 121 ± 3 | 125 ± 4 | 2 ± 2 | −2 ± 2 | 0.16 | |
| SD, mg/dl | 21.2 ± 1.5 | 22.4 ± 2.0 | 1.1 ± 1.2 | −0.5 ± 0.8 | 0.27 | |
| TIR (70–140 mg/dl), % | 80.5 ± 3.1 | 76.6 ± 4.4 | −2.7 ± 2.5 | 1.8 ± 2.0 | 0.17 | |
| TAR (> 140 mg/dl), % | 18.7 ± 3.1 | 23.0 ± 4.4 | 3.0 ± 2.5 | −1.6 ± 2.0 | 0.16 | |
| TBR (< 70 mg/dl), % | 0.8 ± 0.4 | 0.4 ± 0.2 | −0.3 ± 0.6 | −0.2 ± 0.2 | 0.95 | |
| Pre-breakfast | ||||||
| Mean, mg/dl | 107 ± 3 | 110 ± 3 | 2 ± 2 | −2 ± 3 | 0.17 | |
| SD, mg/dl | 4.2 ± 0.4 | 5.2 ± 0.5 | 0.6 ± 0.5 | −1.1 ± 0.5# | 0.013 | |
| Post-breakfast | ||||||
| tAUC, mg/dl × 180 min | 4831 ± 161 | 5009 ± 215 | 287 ± 122* | −104 ± 73## | 0.008 | |
Values are the mean ± standard deviation (SD) for age and height and the mean ± standard error (SE) for other variables
CNT the white rice group, HPR the high-pressure-processed rice group, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, estimated peak aerobic capacity for walking, HRpeak peak heart rate at , LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, TG triglycerides, [Glc]fast fasting blood glucose concentration, HbA1c hemoglobin A1c, CGM [Glc] blood glucose concentration measured by continuous glucose monitoring, TIR time in range, TAR time above range, TBR time below range, tAUC total area under the curve, NA not applicable
aCGM [Glc] data were presented for 24 subjects in the HPR group
bInteractive effect of group x time (before vs. after intervention)
Significant differences from pre-intervention value, *P < 0.05 and **P < 0.01. Significant differences from the corresponding values in the CNT group, #P < 0.05 and ##P < 0.01