Table 2.

Frequencies of QRDRs mutation amongst E.coli isolate highlighting co-occurrence of amino acid substitution within gyrase A (gyrA) and topoisomerase IV (parC).

QRDRs mutations (N)	Isolates N (%)	Amino acid substitution
		N (%)	GyrA	ParC
1	11 (16,41%)	7(10,44%) 1(1,49%) 1(1,49%) 2(1,49%)	S83L S83T S83Y D87N	- - - -
2	11 (16,41%)	5(7,46%) 4(5,97%) 1(1,49%) 1(1,49%)	S83L + D87N S83L S83W D87N	- S80I S80I S80I
3	36 (53,73%)	35(52,23%) 1(1,49%)	S83L + D87N S83L + D87N	S80I E84K
4	9 (13,43%)	7(10,44%) 1(1,49%) 1(1,49%)	S83L + D87N S83L + D87N S83L + D87N	S80I + E84V S80L + E84V S80I + E84G

S: Serine; L: Leucine; I: Isoleucine; D: Aspartate; N: Asparagine; T: Threonine; Y: Tyrosine; W: Tryptophan; E: Glutamic acid; G: Glysine; V: Valine; K: Lysine.