Table 3.

Characterization of E. coli isolates grouped on Profil I in terms of phenotypic resistance and its genotypic basis, phylogenetic groups, and clonal relatedness.

Strains	Qs -FQs resistance phenotypes NAL NXN OFX CIP	Qs-FQs MICs (mg/L)			ATB resistance profiles		QRDRs mutations			PMQRs gene	Phylogenetic group	ST131 clone	PFGE pulsotype/subtype
		NAL S ≤ 16 R > 16	OFX S ≤ 0.25 R > 0.5	C.I.P. S ≤ 0.25 R > 0.5	ß-lactams	Aminoglycosides	Other	gyrA	parC
E. coli (1)	RSSS	24	0.24	0.24	AMP, TIC, PIP	-	-	WP	WP	qnrS1	B2	+	Pulsotype I
E. coli (2)	RSSS	24	0.24	0.24	AMP, TIC, PIP	-	-	WP	WP	qnrS1	B2	+	Pulsotype I
E.coli (3)	RSSS	24	0.24	0.24	AMP, TIC, PIP	-	CHL, SXT	WP	WP	qnrB19	Unknown	-	-
E. coli (4)	RSSS	24	0.24	0.24	AMP, TIC, PIP, AMC, TCC, MEC	-	-	WP	WP	qnrB81	Clade I or II	-	-
E.coli (5)	RSSS	24	0.24	0.24	AMP, TIC, PIP	-	SXT	WP	WP	qnrB	B2	+	Pulsotype VII
E.coli (6)	RSSS	24	0.24	0.24	AMP, TIC, PIP	-	SXT	WP	WP	qnrS15	B2	+	Subtype VIIIb

MICs: minimum inhibitory concentration levels; S: sensitive ; R: resistant; NAL: Nalidixic acid, NXN: Norfloxacin, OFX: ofloxacin; CIP: ciprofloxacin; AMP: ampicillin; TIC: ticarcillin; PIP: piperacillin; TCC : Ticarcillin + Ac.clavulanic; MEC: mecillinam; CHL: chloramphenicol; SXT: co- trimoxazole; RPF: plasmid resistance to fluoroquinolones, QRDRs: quinolone resistance determining region, R: resistant; S: sensitive; WP: wild phenotype, +: positive; -: Negative.