Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
“Cartilage degradation,” “Subchondral bone changes,” and “Synovial inflammation.” Each stage should include key elements: (1) cartilage degradation: loss of proteoglycans, collagen breakdown, and chondrocyte apoptosis. (2) Subchondral bone changes: bone sclerosis, osteophyte formation, and bone marrow lesions. (3) Synovial.
