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. 2024 Nov 27;5:62. doi: 10.1186/s43556-024-00221-y

Table 4.

List of PA bioepitope-related gene names, PAO1 numbers, molecular weights, positions in PAO1, lengths and functions (http://pseudomonas.com)

Gene PAO1 Gene number molecular weight (kDa) location length (bp) function reference
algU PA0762 22.2 831,301..831882 ( +) 582 Regulates genes and affects a variety of physiological processes such as polysaccharide synthesis [177]
lasR PA1430 26.6 1,558,171..1558890 ( +) 720 quorum sensing induction regulator, regulates genes related to bioepithelial membrane formation [178]
rhlR PA3477 27.6 3,889,925..3890650 (-) 726 quorum sensing induction regulator, synergistic with lasR [178]
bfmR PA4101 28 4,585,149..4585889 ( +) 741 Regulation of extracellular polysaccharide synthesis and biofilm formation
pelA PA3064 104.9 3,431,045..3433891 (-) 2847 Involved in the synthesis of the extracellular polysaccharide Pel [179]
pelB PA3063 135.1 3,427,486..3431067 (-) 3582 /
pelC PA3062 18.7 3,426,928..3427446 (-) 519 /
pslA PA2231 54.8 2,453,667..2455103 (+) 1437 Involved in the synthesis of the extracellular polysaccharide Psl, which affects the stability of biological periplasmic membranes [180]
pslB PA2232 53.5 2,455,103..2456569 (+) 1467 /
pslC PA2233 33.6 2,456,569..2457480 (+) 912 /
algD PA3540 47.6 3,962,825..3964135 (+) 1311 Enzymes in the extracellular polysaccharide alginate synthesis pathway [181]
algT PA0762 22.2 831,301..831882 (+) 582 Transcription factor that regulates alginate synthesis [182]
mexS PA2491 36.8 2,806,350..2807369 (-) 1020 Involved in regulating the expression of multidrug efflux pumps [136]