Table 4.

Binding Affinity of ligands with selected Coxsackievirus vital protein receptors.

No	Ligands	Binding Affinity (kcal mol−1)
		Coxsackievirus adenovirus receptor	3C-protease from coxsackievirus B4	3Dpol RNA dependent RNA polymerase
		(PDB: ID 2J12)	(PDB: ID 8Y2U)	(PDB: ID 3DDK)
1	11a	−5.80	−8.10	−8.50
2	11b	−6.50	−9.50	−9.50
3	11c	−6.30	−9.40	−9.40
4	13	−5.70	−5.60	−8.10
5	3	−4.75	−6.50	−7.30
6	7a	−6.80	−9.70	−10.90
7	7b	−5.60	−8.50	−9.30
8	7c	−6.80	−9.30	−9.80
9	7d	−4.50	−8.85	−9.00
10	9a	−4.80	−7.10	−8.60
11	9b	−4.50	−7.15	−8.50
12	Pleconaril	−5.70	−6.10	−7.80