Table 6.

Prediction of toxicity risks and oral toxicity prediction results of compounds.

No	Ligand	Toxicity risks				Physicochemical properties
		Mutagenic	Tumorigenic	Irritant	Reproductive	CLogP	Solubility	Molecular Weight	Drug likeness	Drug score
1	7a	(-)	(-)	(-)	(-)	14.31	−12.13	724.0	−4.55	0.35
2	7c	(+)	(+)	(-)	(-)	15.52	−13.60	792.0	−3.35	0.15
3	11b	(-)	(-)	(-)	(-)	10.33	−7.95	660.0	0.71	0.25
4	11c	(+)	(+)	(-)	(-)	9.52	−6.86	516.0	3.51	0.12