TABLE 1.
Effects of immunization with three immunogenic peptides from T. crassiceps recombinant protective antigen KETc7 on individual parasite intensities
| Group | Mean intensity ± SD (no. of mice with no cysts)a
|
|||
|---|---|---|---|---|
| No peptide | Peptide (μg/mouse)
|
|||
| 0.5 | 10 | 50 | ||
| Control | 14 ± 8.19 | |||
| Immunized with: | ||||
| GK-1 | 9.4 ± 10.9 (0) | 12.4 ± 14.3 (1) | 3.8 ± 5.8b (3) | |
| GK-2 | 13.0 ± 7.9 (0) | 9..2 ± 4.9 (0) | 7.4 ± 2.7 (0) | |
| GK-3 | 14.4 ± 5.81 (0) | 6.7 ± 4.14 (0) | 7.4 ± 2.0 (0) | |
a
Individual parasite intensity (i.e., number of cysticerci in each mouse) in groups of five mice. Groups of five male mice each were immunized with FCA (controls) or the indicated peptides in FCA and challenged 15 days after the second immunization. Thirty days after challenge, mice were sacrificed and the parasite intensity was determined.
b
Statistically significant difference between control and immunized mice at 95% confidence interval (P < 0.05).