Table I.
Clinical characteristics of patients with breast myeloid sarcoma from 2014 to 2022.
| First author/s, year | Patient | Age, years | First symptom | Tumor location | Tumor size | AML link | CD43, CD34 | CD117, MPO | Treatment | Survival | (Refs.) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Naamo, 2022 | P1 | 27 | Painless breast mass | Right breast upper | 65×34×64 mm | No | (+), (+) | (+), (+) | Chemotherapy with Cytosar, Cerubidine and Mylotarg | Alive, 12 months | (15) |
| Amiraian, 2022 | P2 | 63 | Rapidly enlarging breast masses | Multiple lumps in both breasts | - | Yes | (++), (++) | -, (+) | Salvage chemotherapy, allogeneic bone marrow transplant | Deceased, 2 years 9 months | (16) |
| Ding, 2022 | P3 | 34 | Painless breast mass | Right breast | 31×1.5 mm | Yes | -, - | -, (+) | Chemotherapy after surgery and radiotherapy | Alive, 7 years | (17) |
| Huang, 2021 | P4 | 34 | Rapidly enlarging breast masses | Multiple lumps in both breasts | - | Yes | (+++), (+++) | (+), (+) | Chemotherapy | Deceased, 1 year | (18) |
| Varol, 2021 | P5 | 31 | Painless breast mass | Multiple lumps in both breasts | - | Yes | (+), (+) | (+), (+) | Systemic chemotherapy | Alive, 4 years | (19) |
| Kim and Kim, 2019 | P6 | 24 | Painless breast mass | Upper right breast | 43 mm | Yes | -, - | -, (+) | - | Alive, 1 year 6 months | (20) |
| Wu, 2019 | P7 | 42 | Painless breast mass | Upper right breast | 20×18 mm | No | -, - | -, (+) | 2 cycles of IA regimen chemotherapy after surgery | Alive, 1 year | (21) |
| Gomaa, 2018 | P8 | 29 | Painless breast mass | Upper left breast | 15×12×4 mm | No | -, (+) | (+), (−) | Radiotherapy and chemotherapy | Alive, 6 months | (22) |
| Uhida, 2016 | P9 | 28 | Painless breast mass | Right breast | - | No | -, - | -, - | Induction chemotherapy and stem cell transplantation | Deceased, 1 year | (23) |
| Stewart, 2015 | P10 | 46 | Enlarging, tender breast mass | Upper right breast | 44 mm | Yes | -, (+) | (+), (+) | - | N/A | (24) |
| Nalwa, 2015 | P11 | 33 | Painless breast mass | Left breast | - | No | -, (+) | (+),- | High dose cytarabine (HDAC) regimen | Alive, 1 year | (25) |
| Gunduz, 2014 | P12 | 33 | Painless breast mass | Upper right breast | 33 mm | Yes | -, - | -, - | Ara-C, etoposide and idarubicin chemotherapy | Deceased, 1 year 6 months | (26) |
| Fu and Luo, 2014 | P13 | 59 | Painless breast mass | Upper left breast | 18×12 mm | No | -, - | -, (+) | Chemotherapy with the MA regimen and consolidation chemotherapy | Alive, 4 years | (27) |
| Fu and Luo, 2014 | P14 | 39 | Painless breast mass | Lower left breast | 20×15 mm | No | -, - | -, (+) | Succumbed to fungal pneumonia without systemic chemotherapy | Deceased, 4 months | (27) |
Ara-C, cytarabine; HDAC, high-dose Ara-C; MA, mitoxantrone and Ara-C; N/A, not available.