Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Nov 18;31(2):31. doi: 10.3892/mmr.2024.13397

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © 2024 Jiao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 3. — Interaction between MDM2 and PTEN. (A) The interaction between MDM2 and PTEN analyzed by STRING. (B) The binding of MDM2 and PTEN detected by co-immunoprecipitation. (C) The expression of PTEN in HUVECs treated with 40 µg/ml ox-LDL detected by RT-qPCR. (D) The effect of MDM2 knockdown on the transcription expression of PTEN detected by RT-qPCR. (E) The effect of MDM2 knockdown on the protein expression of PTEN detected by western blotting. **P<0.01, ***P<0.001. MDM2, murine double minute-2; PTEN, phosphatase and tensin homolog; STRING, Search Tool for the Retrieval of Interacting Genes/Proteins; ox-LDL, oxidized low-density lipoproteins; IP, immunoprecipitation; RT-q-PCR, reverse transcription-quantitative PCR; si, short interfering; NC, negative control.