Table 1.
Patient Characteristics | Training group (n = 118) | Validation group (n = 53) | Testing group (n = 185) | P value |
---|---|---|---|---|
Age at diagnosis (years) | 68.53 ± 5.93 | 68.36 ± 6.44 | 69.87 ± 6.76 | 0.868a/0.078b/0.148c |
BMI (kg/m2) | 23.86 ± 2.69 | 23.06 ± 2.62 | 23.83 ± 4.01 | 0.071a/0.962b/0.185c |
Initial PSA at diagnosis (ng/ml) | 21.24 (8.09–97.04) | 20.86 (6.20–48.87) | 21.43 (6.46–54.67) | 0.412a/0.074b/0.616c |
Pathological T stage | 0.001a/0.001b/0.291c | |||
≤ pT2c | 81 (68.64%) | 22 (41.51%) | 92 (49.72%) | |
≥ pT3 | 37 (31.36%) | 31 (58.49%) | 93 (50.27%) | |
ISUP grading group of surgical specimens | 0.872a/0.766b/0.957c | |||
≤ 3 | 63 (53.39%) | 29 (54.72%) | 102 (55.13%) | |
>3 | 55 (46.61%) | 24 (45.28%) | 83 (44.97%) | |
Lymph nodes metastasis | 0.281a/0.603b/0.109c | |||
Yes | 13 (11.00%) | 9 (17.00%) | 17 (9.21%) | |
No | 105 (89.00%) | 44 (83.00%) | 168 (90.89%) | |
Positive surgical margin | 0.775a/0.486b/0.410c | |||
Yes | 45 (38.14%) | 19 (35.85%) | 78 (42.17%) | |
No | 73 (61.87%) | 34 (64.15%) | 107 (53.83%) | |
Peri-prostatic fat involvement | 0.646a/0.726b/0.850c | |||
Yes | 3 (2.54%) | 2 (3.77%) | 6 (3.25%) | |
No | 115 (97.46%) | 51 (96.23%) | 179 (96.75%) | |
Perineal invasion | 0.981a/0.677b/0.773c | |||
Yes | 11 (9.32%) | 5 (9.43%) | 20 (11.85%) | |
No | 107 (90.68%) | 48 (90.57%) | 165 (89.15%) | |
Lymphovascular invasion | 0.686a/0.704b/0.484c | |||
Yes | 16 (13.56%) | 6 (11.32%) | 27 (15.13%) | |
No | 102 (86.44%) | 47 (88.68%) | 158 (84.86%) | |
Biochemical recurrence | 0.160a/0.521b/0.318c | |||
Yes | 36 (30.51%) | 22 (41.51%) | 63 (34.05%) | |
No | 82 (69.49%) | 31 (58.49%) | 122 (65.95%) | |
Median Follow-up (months) | 52.01 (44.61–59.41) | 53 (47.07–59.22) | 49.44 (44.16–54.84) |
PCa Prostate cancer, BMI Body mass index, PSA Prostate-specific antigen, ISUP International Society of Urological Pathology
aTraining group vs. Validation group
bTraining group vs. Testing group
cValidation group vs. Testing group