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. 2024 Nov 27;24:1459. doi: 10.1186/s12885-024-13207-4

Table 1.

Baseline characteristics of 356 PCa patients

Patient Characteristics Training group (n = 118) Validation group (n = 53) Testing group (n = 185) P value
Age at diagnosis (years) 68.53 ± 5.93 68.36 ± 6.44 69.87 ± 6.76 0.868a/0.078b/0.148c
BMI (kg/m2) 23.86 ± 2.69 23.06 ± 2.62 23.83 ± 4.01 0.071a/0.962b/0.185c
Initial PSA at diagnosis (ng/ml) 21.24 (8.09–97.04) 20.86 (6.20–48.87) 21.43 (6.46–54.67) 0.412a/0.074b/0.616c
Pathological T stage 0.001a/0.001b/0.291c
 ≤ pT2c 81 (68.64%) 22 (41.51%) 92 (49.72%)
 ≥ pT3 37 (31.36%) 31 (58.49%) 93 (50.27%)
ISUP grading group of surgical specimens 0.872a/0.766b/0.957c
 ≤ 3 63 (53.39%) 29 (54.72%) 102 (55.13%)
 >3 55 (46.61%) 24 (45.28%) 83 (44.97%)
Lymph nodes metastasis 0.281a/0.603b/0.109c
 Yes 13 (11.00%) 9 (17.00%) 17 (9.21%)
 No 105 (89.00%) 44 (83.00%) 168 (90.89%)
Positive surgical margin 0.775a/0.486b/0.410c
 Yes 45 (38.14%) 19 (35.85%) 78 (42.17%)
 No 73 (61.87%) 34 (64.15%) 107 (53.83%)
Peri-prostatic fat involvement 0.646a/0.726b/0.850c
 Yes 3 (2.54%) 2 (3.77%) 6 (3.25%)
 No 115 (97.46%) 51 (96.23%) 179 (96.75%)
Perineal invasion 0.981a/0.677b/0.773c
 Yes 11 (9.32%) 5 (9.43%) 20 (11.85%)
 No 107 (90.68%) 48 (90.57%) 165 (89.15%)
Lymphovascular invasion 0.686a/0.704b/0.484c
 Yes 16 (13.56%) 6 (11.32%) 27 (15.13%)
 No 102 (86.44%) 47 (88.68%) 158 (84.86%)
Biochemical recurrence 0.160a/0.521b/0.318c
 Yes 36 (30.51%) 22 (41.51%) 63 (34.05%)
 No 82 (69.49%) 31 (58.49%) 122 (65.95%)
Median Follow-up (months) 52.01 (44.61–59.41) 53 (47.07–59.22) 49.44 (44.16–54.84)

PCa Prostate cancer, BMI Body mass index, PSA Prostate-specific antigen, ISUP International Society of Urological Pathology

aTraining group vs. Validation group

bTraining group vs. Testing group

cValidation group vs. Testing group