Table 4.
Univariate and multivariate Cox regression analyses exploring prognostic factors for predicting bRFS in patients with non-metastatic PCa receiving RP treatment
| Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Age at diagnosis | 1.017 (0.961–1.076) | 0.549 | - | - |
| BMI | 0.931 (0.825–1.050) | 0.244 | - | - |
| Initial PSA at diagnosis | 1.024 (1.007–1.042) | 0.005 | 1.017 (0.997–1.039) | 0.102 |
| Pathological T stage | 2.780 (1.438–5.374) | 0.002 | 3.006 (1.527–5.918) | 0.001 |
| ISUP grading group of surgical specimens | 3.466 (1.699–7.069) | < 0.001 | 3.575 (1.700–7.519) | < 0.001 |
| Positive surgical margin | 4.401 (2.215–8.744) | < 0.001 | 3.96 (1.950–8.062) | < 0.001 |
| Lymph nodes metastasis | 1.005 (0.355–2.847) | 0.992 | - | - |
bRFS biochemical recurrence-free survival, PCa Prostate cancer, RP radical prostatectomy, HR Hazard ratio, CI Confidence interval, BMI Body mass index, PSA Prostate-specific antigen, ISUP International Society of Urological Pathology