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. 2024 Nov 27;25:426. doi: 10.1186/s12882-024-03876-5

Table 4.

Associations in univariate and multivariable models with [PIVKA-II] as the dependent variable

Univariate model Multivariable model (total r2 = 0.01)
β (95% CI) r 2 P-value β (95% CI) P-value VIF
Age (years) 0.001 (-0.006 to 0.008) 0.00 0.728 0.001 (-0.006 to 0.008) 0.824 1.07
Gender (female) 0.013 (-0.158 to 0.186) 0.00 0.878 0.032 (-0.148 to 0.212) 0.724 1.06
Diabetes (yes) -0.056 (-0.212 to 0.100) 0.00 0.478 -0.059 (-0.222 to 0.105) 0.481 1.05
Smoking (never vs. former or current) 0.083 (-0.074 to 0.241) 0.01 0.300 0.085 (-0.079 to 0.249) 0.307 1.02
[eGFR] (ml/min/1.73 m2) -0.018 (-0.112 to 0.077) 0.00 0.713 -0.048 (-0.168 to 0.071) 0.425 1.57
[Calcium-ion x phosphate] (mmol2/l)2 -0.036 (-0.331 to 0.259) 0.00 0.810 -0.120 (-0.505 to 0.265) 0.539 1.67

CI, confidence interval; [], Logarithmically transformed (natural logarithm); eGFR, estimated glomerular filtration rate; PIVKA-II, protein induced by vitamin K absence II; VIF: variance inflation factor