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. 2024 Nov 27;25:426. doi: 10.1186/s12882-024-03876-5

Table 5.

Associations in univariate and multivariable models with [aortic Agatston score] as the dependent variable

Univariate model Multivariable model (total r2 = 0.38)
β (95% CI) r 2 P-value β (95% CI) P-value VIF
Age (years) 0.07 (0.05 to 0.09) 0.23 < 0.001 0.07 (0.05 to 0.09) < 0.001 1.07
Gender (female) 0.32 (-0.27 to 0.91) 0.01 0.28 0.23 (-0.27 to 0.73) 0.36 1.06
Diabetes (yes) 0.26 (-0.27 to 0.80) 0.01 0.33 0.28 (-0.21 to 0.72) 0.28 1.11
Smoking (never vs. former or current) 0.56 (0.02 to 1.10) 0.03 0.04 0.53 (0.08 to 0.99) 0.02 1.03
[eGFR] (ml/min/1.73 m2) -0.36 (-0.68 to -0.05) 0.03 0.03 -0.47 (-0.88 to -0.05) 0.03 2.45
[PIVKA-II] (ng/ml) 0.71 (0.15 to 1.28) 0.04 0.01 0.64 (0.14 to 1.13) 0.01 1.10
[dp-ucMGP] (pmol/l) 0.44 (-0.05 to 0.93) 0.02 0.08 -0.16 (-0.73 to 0.41) 0.59 1.94
[Calcium-ion x Phosphate] (mmol2/l2) 0.21 (-0.45 to 0.88) 0.00 0.53 0.33 (-0.75 to 1.40) 0.55 1.71

CI, confidence interval; [], Logarithmically transformed (natural logarithm); VIF, Variance inflation factor; eGFR, estimated glomerular filtration rate; PIVKA-II, protein induced by vitamin K absence II; dp-ucMGP, dephosphorylated uncarboxylated matrix gla protein; VIF: Variance inflation factor