Table 1.
Program performance using a variety of settings
| Sensitivity (%) | Positive predicative value (%) | Accuracy (%) | |
|---|---|---|---|
| Plain | 83 | 86.5 | 85 |
| Weighted amino acids | 84 | 90.3 | 87.5 |
| Evolutionary information | 89 | 93.7 | 91.5 |
| Evolutionary information + weighted amino acids | 91 | 93.8 | 92.5 |
The ability of TMB-Hunt to discriminate between BTM and NTM proteins, tested using the ‘leave homologues out’ cross-validation method and with a range of different features.