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. 2024 Nov 8;9(21):e173052. doi: 10.1172/jci.insight.173052

Figure 7. Auditory brainstem responses (ABR) and vestibular-evoked potentials (VsEP) after artificial perilymph, curare, or CNQX injections through the PSCC.

Figure 7

(A) Representative traces of ABR recordings 1 hour after injection of artificial perilymph (AP), curare (1 mM), or CNQX (100 μM). Responses are shown for stimulus intensity from 20 to 80 dB SPL in 10-dB SPL increments. (B) Representative traces of VsEP measurements from the same animals as in panel A with stimuli varying between 0.1 and 2.0 g/ms. Red traces indicate thresholds. Scale bars: 1 μV. Summary data for (C) ABR (n = 8) and (D) VsEP (n = 8) show preinjection (black) and 1 hour after injection (red) symbols for individual animals. Boxes, SD; stars, mean; lines, median. ***P < 0.001 by paired, 2-tailed Student’s t test for the CNQX treatment for both ABR and VsEP.