Figure 2. Verification of the cell specificity of the microglia-specific Gba-KO mouse.

Tmem119-Cre mice were crossed with tdTomato reporter mice. Tmem119-Cre drives the specific expression of tdTomato in microglia (Iba1 labeled) but not in neurons (NeuN labeled), oligodendrocytes (Olig2 labeled), or astrocytes (GFAP labeled). All images (other than tile scans) are from the cortex. Scale bars: 1 mm (tile scan); 20 μm (bottom 3 rows). n = 3.