Skip to main content
. 2024 Nov 8;9(21):e179126. doi: 10.1172/jci.insight.179126

Figure 5. GlcCer and GlcSph levels are elevated in Gba-nKO and Gba-wbKO mice.

Figure 5

Gba-mKO, -nKO, and -wbKO brains were collected at 12 months, 16 weeks, and 7–8 weeks, respectively. (A) Total GlcCer levels in the brains of Gba-mKO, Gba-nKO, and Gba-wbKO mice. Unpaired t test. (B) GlcSph levels in the brains of Gba-mKO, Gba-nKO, and Gba-wbKO mice. Unpaired t test. (C) Individual GlcCer species in the brains of Gba-mKO, Gba-nKO, and Gba-wbKO mice. Two-way ANOVA and Holm-Šidák’s multiple comparisons test. n = 5. **P < 0.01, ***P < 0.001, ****P < 0.0001.