Figure 2:

Social proximity-induced GCaMP and GRAB_DA activity in the aIC.

SS paired subjects (A) and OS paired subjects (B) show differing patterns of close proximity to partners vs strangers across testing days. GCaMP relative fluorescence during close proximity to partners vs strangers in SS and OS paired subjects during social exposure tests on experimental Day 0 (C), Day 2 (D), and Day 8 (E) with corresponding area under the curve (AUC) calculations (F-H). GRAB_DA relative fluorescence during close proximity to partners vs strangers in SS and OS paired subjects during social exposure tests on Day 0 (I), Day 2 (J), and Day 8 (K) with corresponding AUC calculations (L-N). ^denotes p<0.05 for partner vs stranger within pairing group, *denotes p<0.05 for SS vs OS pairing condition within the same social stimulus type.