Figure 3:

Olfactory investigation-induces GCaMP and GRAB_DA activity in the aIC.

SS paired subjects (A) and OS paired subjects (B) do not significantly differ in their patterns of olfactory investigation of partners vs strangers across testing days. GCaMP relative fluorescence during olfactory investigation of partners vs strangers in SS and OS paired subjects during social exposure tests on experimental Day 0 (C), Day 2 (D), and Day 8 (E) with corresponding area under the curve (AUC) calculations (F-H). GRAB_DA relative fluorescence during olfactory investigation of partners vs strangers in SS and OS paired subjects during social exposure tests on Day 0 (I), Day 2 (J), and Day 8 (K) with corresponding AUC calculations (L-N). ^denotes p<0.05 for partner vs stranger within pairing group, *denotes p<0.05 for SS vs OS pairing condition within the same social stimulus type.