Table 1:
Frequency of ANA reactivities in SLE patients with low versus high PB/M ratios. Positivity of ANA-IgG for each indicated antigen was determined using ELISA. Anti-chromatin refers to all patients positive for 1 or more of the antigens dsDNA, Nucleosomes, and histones. Anti-Sm/RNP refers to all patients positive for 1 or more of the antigens Sm, and RNP70. Anti-SS-A/B refers to all patients positive for 1 or more of the antigens SS-A, and SS-B (all patients with SS-B were also positive for SS-A).
P values were obtained using Fisher’s exact test.
| Low PB/M ratio (n=30) |
High PB/M ratio (n=39) |
Odds Ratio | p value | |
|---|---|---|---|---|
| Anti-chromatin | 17 (57%) | 21 (54%) | 0.89 (0.33-2.31) | >0.9999 |
| dsDNA | 15 (50%) | 21 (54%) | 1.17 (0.45-3.05) | 0.8108 |
| Nucleosomes | 4 (13%) | 9 (23%) | 1.95 (0.60-6.21) | 0.3650 |
| Histones | 5 (17%) | 9 (23%) | 1.50 (0.46-4.57) | 0.5612 |
| Anti-Sm/RNP | 9 (30%) | 30 (77%) | 7.78 (2.59-20.83) | 0.0002 *** |
| Sm | 6 (20%) | 20 (51%) | 4.21 (1.39-13.09) | 0.0118 * |
| RNP70 | 2 (7%) | 20 (51%) | 14.74 (3.26-67.25) | <0.0001 **** |
| U1-Sm/RNP | 8 (27%) | 27 (69%) | 6.19 (2.14-16.08) | 0.0006 *** |
| Anti-SS-A/B | 17 (57%) | 24 (62%) | 1.22 (0.45-3.29) | 0.8056 |
| SS-A | 17 (57%) | 24 (62%) | 1.22 (0.45-3.29) | 0.8056 |
| SS-B | 2 (7%) | 6 (15%) | 2.55 (0.56-13.02) | 0.4509 |