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[Preprint]. 2024 Nov 21:2024.11.20.623809. [Version 1] doi: 10.1101/2024.11.20.623809

Figure 2. Islet secretory function is highly heterogeneous amongst donors.

Figure 2.

Average (A) insulin and (B) glucagon secretion from donor islets normalized to islet equivalents (IEQs). Data are displayed as mean ± 95% confidence interval (n = 299). (C) Schematic and tables describing insulin and (D) glucagon secretion traits derived from individual islet secretion traces. Descriptive statistics by sex and reported race/ethnicity are provided in Extended Data Tables 1 and 2. G – Glucose (mM); IBMX – isobutylmethylxanthine (μM); A – adrenaline (μM); KCl – potassium chloride (mM).