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Serum and salivary immune responses to HDS after subcutaneous injection with PQW, EAW, or HDS peptide constructs or S. mutans GTF
| Injected group | Mean EU ± SE (n = 4–7 rats/group)a
|
|||||
|---|---|---|---|---|---|---|
| Serum IgG
|
Salivary IgA
|
|||||
| Pre | Day 42 | Range | Pre | Day 42 | Range | |
| Sham | 0 ± 0 | 0 ± 0 | 0 | 1 ± 1 | 0 ± 0 | 0 |
| PQW | 0 ± 0 | 0 ± 0 | 0 | 0 ± 0 | 1 ± 1 | 0–1 |
| EAW | ND | 0 ± 0 | 0 | ND | ND | |
| HDS | 0 ± 0 | 118 ± 18 | 99–155 | 1 ± 1 | 142 ± 36 | 16–206 |
| S. mutans GTF | 0 ± 0 | 0 ± 0 | 0 | 0 ± 0 | 1 ± 1 | 0–3 |
Pre, preimmunization; ND, not done.
