Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

[Preprint]. 2024 Nov 13:2024.11.13.24317257. [Version 1] doi: 10.1101/2024.11.13.24317257

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This work is licensed under a Creative Commons Attribution 4.0 International License, which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use.

PMC Copyright notice

Extended Data Figure 4. — Genotyping and pseudobulk caQTL discovery. (a) PC1 and 2 for genotyping data (post imputation from the TOPMED panel and filtering for variants with imputation R² < 0.3 and MAF > 0.05) panel for each sample. (b) Local ancestry inference (YRI (n=186) and CEU (n=183) from the 1000 Genome Project¹⁰² were used as AFR / EUR reference populations, respectively.) genetic proportion stack plot by sample. (c) Correlation heatmap for ancestry PCs and ATAC count PCs. (d) Multi-trait pseudobulk Manhattan plot for caQTL colored by cell type genome wide. (e) Distance from caQTL to the regulated peak colored by cell type.