TABLE 2.
IgA antibody response against rSm28GST after nasal administration
| Wks | Antibody levela
|
|
|---|---|---|
| PLG-rSm28GST | PCL-rSm28GST | |
| IgA in serum | ||
| 10 | 830 | 930 |
| 30 | 410 | 530 |
| IgA in BAL fluids | ||
| 9 | 270 | 430 |
| 26 | 120 | 200 |
a
The results are given for pools of 10 (at week 10) or 4 (at week 30) mice for sera and 3 mice for BAL fluids. Titers are defined as the highest dilution yielding an absorbance three times above the background (no serum added). For free rSm28GST, empty PLG, and empty-PCL, titers were <20 (serum IgA) or <2 (IgA in BAL fluids).