Table 5.
BY RACE | |||||
---|---|---|---|---|---|
Baseline disease severity, μm | “True” rates of change, μm/year | Mean time to detect progression, Mean ± SD, years | Difference in time to detect progression in 80% of eyes (80% power), years | ||
|
|||||
Black or African American | White | P value | Black or African American versus White Subjects | ||
| |||||
90 | −0.5 | 10.2 ± 5.3 | 10.0 ± 5.3 | 0.291 | 0.2 |
|
|||||
−1.0 | 6.6 ± 2.3 | 6.4 ± 2.2 | 0.003 | 0.3 | |
|
|||||
−2.0 | 4.7 ±1.4 | 4.4 ±1.4 | 0.000 | 0.3 | |
| |||||
70 | −0.5 | 10.0 ± 5.6 | 9.6 ± 5.7 | 0.184 | 0.2 |
|
|||||
−1.0 | 6.4 ± 2.1 | 5.9 ±1.8 | 0.000 | 0.7 | |
|
|||||
−2.0 | 4.4 ±1.2 | 4.1 ±1.2 | 0.000 | 0.3 | |
| |||||
BY ETHNICITY | |||||
Baseline disease severity, μm | “True” rates of change, μm/year | Mean time to detect progression, Mean ± SD, years | Difference in time to detect progression in 80% of eyes (80% power), years | ||
|
|||||
Hispanic or Latino | Not Hispanic or Latino | P value | Hispanic or Latino versus Not Hispanic or Latino |
||
| |||||
90 | −0.5 | 9.6 ± 5.4 | 10.6 ± 5.7 | 0.000 | −1.3 |
|
|||||
−1.0 | 6.0 ± 2.0 | 6.5 ± 2.2 | 0.000 | −0.7 | |
|
|||||
−2.0 | 4.4 ±1.2 | 4.5 ±1.4 | 0.000 | −0.3 | |
| |||||
70 | −0.5 | 9.4 ± 5.6 | 9.5 ± 5.3 | 0.875 | 0.2 |
|
|||||
−1.0 | 5.9 ± 2.1 | 5.9 ±1.9 | 0.768 | 0.0 | |
|
|||||
−2.0 | 4.2 ±1.1 | 4.2 ±1.2 | 0.383 | 0.0 |
SD = Standard deviation.