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. 2005 Jun 27;33(Web Server issue):W352–W357. doi: 10.1093/nar/gki431

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© The Author 2005. Published by Oxford University Press. All rights reserved

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Dynamic linking for finding topological features. The network of synthetic lethal genetic interactions (28) in yeast contains 823 genes and 3952 interactions. A plot of the degree distribution of genes in this network allows users to quickly identify which genes have the highest (or lowest) connectivity. In this example, the gene shown is YDL029W, which has synthetic lethal interactions with 58 neighbors.