Figure 3. Metabolic responses to dietary intervention.

(A) Volcano plots of paired t tests comparing postchamber metabolite levels with prechamber metabolite levels for select chambers. Results for all chambers are presented in Supplemental Figure 2. (B) Results from paired t tests are summarized for each dietary chamber, grouped by HMDB metabolite class demonstrating glycerophospholipids as the most common class of metabolite to change. (C) Heatmap of the mean log₂ fold change for all metabolites for all dietary chambers, demonstrating similarities between clusters of diets.