Table 2.

Different forms of subunit vaccine trials against sexual stage of Babesia parasite (Transmission blocking vaccine).

Antigen(s)	Efficacy	Reference
Mixed recombinant proteins
B. bovis 6cys A and B	Failed to block transmission in vivo	(52)
Single protein
B. bovis HAP2 (hapless2)	Vaccination blocked Babesia transmission via tick in in vivo experiments performed on immunized cattle.	(147)
B. bigemina HAP2	Anti-HAP2 specific antibodies from immunized animals were able to block zygote formation in vitro for B. bigemina. No in vivo application followed by a challenge described.	(165)
Peptides
B. bovis 6cys A and B	Rabbit anti B. bovis 6cys A and B were able to block B. bovis gametes development in vitro.	(52)