Table 8.
Live vaccines against cattle anaplasmosis.
| Form | Efficacy | Reference |
|---|---|---|
| live virulent A. marginale paired with treatment premunition | Variable. Some vaccinated animals were infected with a delayed incubation period, while other animals showed no clinical signs after vaccination. | (201) |
| Virulent strains of A. marginale attenuated by passaging organisms in unnatural hosts (splenectomized sheep and deer) | Variable. The deer-passaged strain vaccine failed to induce solid protection in vaccinated animals while sheep-attenuated strains induced protection. | (201, 202) |
| Fresh or frozen infected RBCs with A. marginale strains of naturally low virulence | Induced a mild clinical syndrome in the immunized animals | (203, 204) |