Table 1.
Distribution of pathway–node identifiers among the major pathway resources
| Pathway | Gene/protein | ID resolution | Metabolite | Embedded pathway | Free text description | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Simple | Complex | Redundant | Total | OGS | LL | SP | UR | ||||||||
| H.sapiens | |||||||||||||||
| KEGG | 70 | (256)a | (121) | (469) | 740 | 720 | 20 | 0 | 0 | 1896 | (2624) | 0 | (0) | 121 | (275) |
| (505)a | (637) | ||||||||||||||
| 740 | (1106) | ||||||||||||||
| GenMAPP | 45 | 1454 | (1942) | 1391 | 1329 | 39 | 23 | 63 | 83 | (97) | 4 | (4) | 130 | (372) | |
| BioCarta | 346 | 1584 | (8976) | 1584 | 1580 | 4 | 0 | 0 | 0 | (0) | 50 | (141) | 18 | (53) | |
| PharmGKB | 9 | 134 | (189) | 134 | 133 | 1 | 0 | 0 | 11 | (25) | 1 | (1) | 23 | (26) | |
| Overall | 470 | 3088 | (12 900) | 3025 | 2938 | 64 | 23 | 63 | 1990 | (2746) | 55 | (146) | 55 | (146) | |
| M.musculus | |||||||||||||||
| BioCarta | 277 | 1260 | (7646) | 1260 | 1224 | 36 | 0 | 0 | 1 | (1) | 37 | (113) | 75 | (311) | |
| R.norvegicus | |||||||||||||||
| KEGG | 63 | (160) | (72) | (527) | 451 | 282 | 169 | 0 | 0 | 1774 | (2435) | 0 | (0) | 167 | (72) |
| (277) | (753) | ||||||||||||||
| 451 | (1280) | ||||||||||||||
Numbers in parentheses are redundant counts. KEGG has 121 composite elements containing 505 identifiable gene products. OGS, official gene symbol; LL, LocusLink; SP, SwissProt; and UR, unresolved.
aThere were 21 elements redundant in the simple (256) and composite (505) elements so that 740 unique elements were found in the 70 KEGG human pathways.