TABLE 3.

Main studies dealing with the effects of Akkermansia muciniphila in bodyweight management.

Study	Disease	Design	Size	Patients	Length	Outcomes
Dao et al. (2019)	Obesity	Non-randomised prospective study	65	Adults	12 months	A. muciniphila abundance does not affect glucose tolerance and insulin sensitivity in patients after gastric bypass surgery
Shin NR (2014)	Healthy	Animal study	24	HFD-fed mice	6 weeks	A. muciniphila administration reduse adipose tissue inflammation
Depommier et al. (2019)	Overweight and obesity	Randomised double blind study	32	Adults	3 months	Increased A. muciniphila abundance negatively correlates with insulin resistance, inflammation markers and liver disfunction markers
Dao (2016)	Overweight and obesity	Randomised control study	49	Adults	3 months	Increased A. muciniphila abundance positively correlates with insulin sensitivity
Cao et al. (2023)	Obesity	Randomised double blind study	37	Adults	4 months	Increased A. muciniphila abundance positively correlates with weight loss