Table 3.
Infection based on humoral and cellular memory.
| anti-N IgG | Number not infected | Number infected | p-value | |
|---|---|---|---|---|
| Healthy adults | Negative serology | 16 | 7 | >0.9999 |
| Positive serology | 0 | 0 | ||
| Older adults | Negative serology | 14 | 3 | >0.9999 |
| Positive serology | 1 | 0 | ||
| Oncohaematologic patients | Negative serology | 18 | 14 | >0.9999 |
| Positive serology | 1 | 0 | ||
| anti-S IgG | Number not infected | Number infected | p-value | |
| Healthy adults | Negative serology | 0 | 0 | >0.9999 |
| Positive serology | 16 | 7 | ||
| Older adults | Negative serology | 0 | 0 | >0.9999 |
| Positive serology | 15 | 3 | ||
| Oncohaematologic patients | Negative serology | 8 | 8 | 0.4905 |
| Positive serology | 11 | 6 | ||
| anti-S IgA | Number not infected | Number infected | p-value | |
| Healthy adults | Negative serology | 5 | 1 | 0.6214 |
| Positive serology | 11 | 6 | ||
| Older adults | Negative serology | 12 | 3 | >0.9999 |
| Positive serology | 3 | 0 | ||
| Oncohaematologic patients | Negative serology | 12 | 9 | >0.9999 |
| Positive serology | 7 | 5 | ||
| IFN-γ production | Mean | Standard error of the mean | p-value | |
| Healthy adults | Not infected | 5.125 | 0.936 | 0.4346 |
| Infected | 7.071 | 3.087 | ||
| Older adults | Not infected | 5.429 | 1.666 | 0.2258 |
| Infected | 11.33 | 7.126 | ||
| Oncohaematologic patients | Not infected | 7.211 | 1.175 | 0.2313 |
| Infected | 11.13 | 4.142 | ||
For each cohort, the absolute number of infected and non-infected individuals based on their serology status is shown for anti-N IgG and anti-S IgG and IgA. The mean and standard error for IFN-γ production following ELISpot assay towards S is also shown based on subsequent infection. The data were analysed with Fisher’s exact test (humoral memory) or a t-test (cellular memory). A p-value < 0.05 was considered statistically significant.