Software and algorithms |
|
STAR v2.7.1a |
Dobin et al.69
|
https://github.com/alexdobin/STAR |
RNA-SeQC73 v2.3.4 |
DeLuca et al.70
|
https://github.com/francois-a/rnaseqc |
R package: DESeq2 v1.30.0 |
Love et al.71
|
https://bioconductor.org/packages/release/bioc/html/DESeq2.html |
BCFtools v1.6 |
Danecek et al.72
|
https://www.htslib.org/download/ |
PLINK v1.90b6.10 |
Purcell et al.73
|
https://www.cog-genomics.org/plink/ |
R package: edgeR v3.32.1 |
Robinson et al.74
|
https://bioconductor.org/packages/release/bioc/html/edgeR.html |
R package: topGO |
Alexa et al.75
|
https://bioconductor.org/packages/release/bioc/html/topGO.html |
BisqueRNA R package |
Jew et al.27
|
https://github.com/cran/BisqueRNA |
APEX toolkit |
Quick et al.76
|
https://github.com/corbinq/apex |
R package: coloc |
Giambartolomei et al.77
|
https://cloud.r-project.org/web/packages/coloc/index.html |
R package: mashR |
Urbut et al.40
|
https://github.com/stephenslab/mashr |
BURST version 0.99.7f96 |
Al-Ghalith et al.78
|
https://github.com/knights-lab/BURST |
MetaPhlAn v3.0.7 |
Beghini et al.79
|
https://huttenhower.sph.harvard.edu/metaphlan/ |
Sparse canonical components analysis code |
Priya et al.53
|
https://github.com/blekhmanlab/host_gene_microbiome_interactions |
CoPTR |
Joseph et al.61
|
https://github.com/tyjo/coptr |
|
Deposited data |
|
Milk RNA-sequencing data |
This paper |
dbGaP: phs003408.v1.p1 |
Milk DNA-sequencing data and genotypes |
This paper |
dbGaP: phs003408.v1.p1 |
Infant fecal metagenomic sequencing data |
This paper |
SRA: PRJNA1019702 |
Milk transcriptome quantifications, infant fecal metagenome abundances, milk eQTL summary statistics, HMO concentrations, additional metadata |
This paper |
https://figshare.com/collections/Johnson_et_al_human_milk_multi-omics/7371256 |
GTEx RNA-sequencing quantifications and eQTL summary statistics |
GTEx Portal25
|
https://gtexportal.org/home/downloads/adult-gtex/overview |
1000 Genomes genotypes |
Byrska-Bishop et al.80
|
https://www.internationalgenome.org/data-portal/data-collection/30x-grch38 |
Single-cell human milk RNA-seq data |
Nyquist et al.17
|
https://singlecell.broadinstitute.org/single_cell/study/SCP1671/cellular-and-transcriptional-diversity-over-the-course-of-human-lactation |
Breast cancer GWAS summary statistics |
Zhang et al.43
|
http://bcac.ccge.medschl.cam.ac.uk/ |