FIGURE 2.

Uniform manifold approximation (UMAP) of 56 906 of profiled cells from both pulmonary long COVID and control groups, which were annotated using legacy markers. Final annotation of the cluster revealed 16 clusters that were of epithelial origin and 15 clusters that were immune cells. a) A dimensionality reduction plot of pulmonary long COVID versus control reveals distribution of clusters across both categories. It prominently highlights a specific cluster derived from the pulmonary long COVID group. b) Various clusters of cells originating from both epithelial and immune cell lineages were observed. As anticipated, the diversity among these identified cell clusters serves as a representation of the cellular heterogeneity within the airway mucosa. Additionally, distinct neutrophil cluster was highlighted. MAIT: mucosal-associated invariant T-cell; TCM: central memory T-cell; NK: natural killer.