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. 2024 Aug 19;90(12):3263–3276. doi: 10.1111/bcp.16199

TABLE 1.

Assessment of osimertinib dependency of ILD events using penalized logistic regression.

Model Intercept (95% CI) Exposure (95% CI) Japanese (95% CI) Asian (non‐Japanese) (95% CI) Change in OBJ
1 −10.3 (−14.5, −5.93) 0.741 (0.288, 1.18) −10.1
2 −9.83 (−14.3, −5.29) 0.649 (0.172, 1.11) 1.42 (0.85, 1.99) −32.7
3 −9.35 (−13.8, −4.76) 0.628 (0.149, 1.09) 1.14 (0.510, 1.80) −0.567 (−1.38, 0.206) −34.3
4 −3.71 (−4.12, −3.35) 1.51 (0.949, 2.08) −25.8

Note: Dashes denote variables that were not included in respective models.

Abbreviations: CI, confidence interval; ILD, interstitial lung disease; OBJ, objective function value.