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| IC50 (μM) |
||
|---|---|---|
| Compound | E. coli DNA gyrase | DHFR E. coli |
| 9d | 217 ± 13 | 5.90 ± 0.20 |
| 9n | 190 ± 11 | 4.60 ± 0.20 |
| 9o | 182 ± 10 | 3.90 ± 0.10 |
| 9p | 205 ± 13 | 5.40 ± 0.20 |
| Novobiocin | 170 ± 10 | -- |
| Trimethoprim | -- | 5.20 ± 0.20 |
