Table 4. Clinical Characteristics of Healthy Volunteers and RA Patientsa,b.
| characteristic | healthy volunteers | RA patients | p-value |
|---|---|---|---|
| number of subjects | 8 | 36 | |
| males/females | 2/6 | 10/26 | >0.9999 |
| age (years) | 24.8 ± 2.77 [22–31] | 65.3 ± 14.0 [24–87] | <0.0001 |
| body weight (kg) | 53.1 ± 6.97 [44.0–65.0] | 53.9 ± 10.6 [28.5–77.0] | 0.803 |
| ALT (IU/L) | 13.3 ± 3.34 [9.0–19.0] | 19.7 ± 15.5 [8.1–90.3] | 0.223 |
| total bilirubin (mg/dL) | 0.600 ± 0.173 [0.40–1.0] | 0.647 ± 0.269 [0.25–1.50] | 0.566 |
| serum creatinine (mg/dL) | 0.596 ± 0.0840 [0.45–0.72] | 0.706 ± 0.138 [0.43–1.01] | 0.0135 |
| DAS28-CRP | 3.36 ± 0.711 [2.20–5.31] |
a
ALT, alanine aminotransaminase; DAS-28-CRP, disease activity score-28-C–reactive protein.
b
Data are expressed as numbers or mean ± standard deviation [range].