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. 2024 Nov 27;9:237. doi: 10.1038/s41541-024-01030-8

Fig. 4. The comparison of rabies virus (RABV) neutralizing antibody (nAb) titers between RABV-exposed versus RABV-unexposed individuals at different timepoints after post-exposure prophylaxis (PEP) using the Institut Pasteur du Cambodge (IPC) regimen.

Fig. 4

The RABV nAb titers of individuals bitten by RABV-positive dogs that received PEP with eRIG (red, n = 78) and individuals bitten by RABV-negative dogs that received PEP without eRIG (blue, n = 67) were measured by fluorescent antibody virus neutralization test (FAVNT) at baseline (D0), day 7 (D7), day 14 (D14), month 6 (M6), and month 12 (M12) after PEP. For visualization purposes, data was transformed into logarithmic scales before being used in statistical analysis. Each dot represents a single individual. Black lines represent the median and interquartile range. Dashed line indicates the threshold of protective RABV nAb titer at 0.5 international unit per milliliter (IU/mL). Statistics: Mann-Whitney test. Asterisks represent significance levels as follows: *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.