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The ts phenotype of paf1Δ, cdc73Δ, ccr4Δ, and gal11Δ can be corrected by the cell wall-stabilizing agent sorbitol. (A) Isogenic wild type (WT; YJJ662), paf1Δ (YJJ664), cdc73Δ (YJJ665), gal11Δ (YJJ564), srb5Δ (YJJ875), ccr4Δ (YJJ879), sin4Δ (YJJ832), and hpr1Δ (YJJ898) strains were grown on YPD or YPD plus 1 M sorbitol at 38°C for 4 days. (B) Isogenic wild-type (WT; YJJ662) and paf1Δ (YJJ664) strains were grown on YPD or YPD plus 1 M sorbitol at 35.5°C for 2.5 days.
