Table 1. Definitions of TNM for ocular adnexal lymphoma, AJCC Cancer Staging Manual, eighth edition.
| Primary tumour (T) | |
| TX | Lymphoma extent not specified |
| T0 | No evidence of lymphoma |
| T1 | Lymphoma involving the conjunctiva alone without eyelid or orbital |
| T2 | Lymphoma with orbital involvement with or without conjunctival involvement |
| T3 | Lymphoma with preseptal eyelid involvement with or without orbital involvement and with or without conjunctival involvement |
| T4 | Orbital adnexal lymphoma and extraorbital lymphoma extending beyond the orbit to adjacent structures, such as bone, maxillofacial sinuses and brain. |
| Regional lymph nodes (N) | |
| NX | Involvement of lymph nodes not assessed |
| N0 | No evidence of lymph node involvement |
| N1 | Involvement of lymph node region or regions draining the ocular adnexal structures and superior to the mediastinum (periauricular, parotid, submandibular and cervical nodes) |
| N1a | Involvement of a single lymph node region superior to the mediastinum |
| N1b | Metastasis in a single ipsilateral regional lymph node based on lymph node biopsy |
| N2 | Metastasis in a single ipsilateral regional lymph node, >3 cm in greatest dimension, or in bilateral or contralateral lymph nodes |
| N3 | Diffuse or disseminated involvement of peripheral and central lymph node regions |
| Distant metastasis (M) | |
| M0 | No evidence of involvement of other extranodal sites |
| M1a | Noncontiguous involvement of tissues or organs external to the ocular adnexa (eg, parotid glands, submandibular gland, lung, liver, spleen, kidney, breast) |
| M1b | Lymphomatous involvement of the bone marrow |
| M1c | Both M1a and M1b involvement |
AJCCAmerican Joint Committee on Cancer