Table 5.
Linear regression analysis - orthostatic DBP reaction in relation to spirometry lung function parameters
| Basic model | Adjustment model 1 | Adjustment model 2 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| β | R2 | p-value | β | R2 | p-value | β | R2 | p-value | ||
| FVC | -4.26 | 0.71 | <0.001 | -4.26 | 0.71 | <0.001 | -3.92 | 0.70 | 0.014 | |
| FEV1 | -2.59 | 0.65 | 0.005 | -2.62 | 0.66 | 0.005 | -2.28 | 0.65 | 0.097 | |
| DLCO | -0.002 | 0.55 | 0.496 | -0.001 | 0.58 | 0.719 | -0.006 | 0.57 | 0.526 | |
A negative β represents a negative correlation between the lung function parameter and orthostatic DBP reaction (e.g. decreasing FVC with decreasing orthostatic DBP)
β = The increase in FVC/FEV1/DLCO for every 1 mmHg decrease in orthostatic DBP reaction
FVC (ml); FEV1 (ml); DLCO (mmol/(min*kPa))
Basic model (adjusted for age, sex and height)
Adjustment model 1 (age, sex, height, current smoking)
Adjustment model 2 (age, sex, height, current smoking, supine SBP, carotid artery plaques, coronary calcium score, antihypertensive drugs, β-blockers, diabetes, inhalation medication for COPD or asthma)