Table 1.
Combined sequencing results for a subset of 74 E. coli and K. pneumoniae isolates and phenotypic MASTDISC D72C results
| Genes | MASTDISCS results (T/C/P) | Total | |||||||
|---|---|---|---|---|---|---|---|---|---|
| AmpC | Inducible AmpC | AmpC and ESBL positive | ESBL positive | Equivocal | Undetermined Group 1 | Undetermined Group 2 | AmpC & ESBL negative | ||
| n = 31 | n = 16 | n = 3 | n = 1 | n = 2 | n = 1 | n = 19 | n = 1 | n = 76 | |
| bla CMY-2 | 20/15/5 | 0 | 0 | 0 | 0 | 0 | 11/10/1 | 0 | 31/25/6 |
| bla CMY-6 | 0 | 0 | 0 | 0 | 2/2/0 | 0 | 0 | 0 | 2/2/0 |
| bla CMY-30 | 1/1/0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1/1/0 |
| bla CMY-42 | 5/0/5 | 0 | 1/0/1 | 0 | 0 | 0 | 3/0/3 | 0 | 9/0/9 |
| bla DHA-1 | 2/1/1 | 16/7/9 | 0 | 0 | 0 | 1/1/0 | 1/1/0 | 0 | 20/10/10 |
| bla NDM-5 | 1/0/1 | 0 | 0 | 0 | 0 | 0 | 16/0/16 | 0 | 17/0/17 |
| bla OXA-1 | 3/0/3 | 2/1/1 | 1/0/1 | 0 | 1/0/1 | 0 | 15/2a/14 | 0 | 23/3/20 |
| bla OXA-48 | 0 | 0 | 0 | 0 | 0 | 1/0/1 | 2/0/2 | 0 | 3/0/3 |
| bla TEM-1 | 25/5/20a | 6/0/6 | 2/0/2 | 1/1/0 | 0 | 0 | 15/1/14a | 1/1/0 | 50/8/42 |
| bla SVH-1 | 1/1/0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1/1/0 |
| bla SVH-11 | 0 | 5/5/0 | 0 | 0 | 0 | 1/1/0 | 1/1/0 | 0 | 7/7/0 |
| bla SVH-28 | 0 | 1/1/0 | 0 | 0 | 0 | 0 | 0 | 0 | 1/1/0 |
| bla SVH-32 | 0 | 1/1/0 | 0 | 0 | 0 | 0 | 0 | 0 | 1/1/0 |
| bla CTX-M-14 | 0 | 0 | 1/0/1 | 1/0/1 | 0 | 0 | 0 | 0 | 2/0/2 |
| bla CTX-M-15 | 2/1/1 | 0 | 1/0/1 | 0 | 2/0/2 | 0 | 14/0/14b | 0 | 19/1/18 |
| bla CTX-M-55 | 0 | 0 | 0 | 0 | 0 | 0 | 2/0/2 | 0 | 2/0/2 |
| bla LAP-2 | 0 | 1/0/1 | 0 | 0 | 0 | 0 | 1/0/1 | 0 | 2/0/2 |
n, number of isolates with a MASTDISC result; T, total amount with gene; C, number found on the chromosome; P, number found on a plasmid; Undetermined Group 1, inducible AmpC suspected carbapenemase or suspected ESBL/AmpC with porin loss; Undetermined Group 2, suspected carbapenemase or suspected ESBL/AmpC with porin loss. Only genes with ≥95% coverage and ≥95% identification with a reference gene are included, unless otherwise stated.
aTruncated gene detected for one isolate.
bTruncated gene detected for two isolates.