Table 1.

Baseline and post-surgery characteristics and clinical parameters

	Baseline	Post-surgery	p-value
Age	44.6 ± 9.4	-	-
Weight (kg)	106.9 ± 12.1	87.0 ± 12.4	<0.001*
BMI (kg/m2)	39.3 ± 5.6	32.0 ± 5.0	<0.001*
Fat mass (kg)	49.5 ± 14.3	31.0 ± 9.2	0.002*
Fat-free mass (kg)	57.4 ± 16.2	56.0 ± 10.8	0.723*
Fat mass (%)	46.5 ± 12.8	35.6 ± 9.7	0.012*
Hip circumference (cm)	127.1 ± 13.8	105.6 ± 13.4	0.004*
Waist circumference (cm)	117.7 ± 11.8	103.1 ± 11.0	<0.001*
HbA1c (%)	6.9 ± 1.0	5.9 ± 0.8	0.009*
Glucose (mmol/L)	6.3 (2.0)	5.3 (1.0)	0.375**
Insulin (mU/L)	16.8 ± 9.3	7.0 ± 4.2	0.018*
Creatinine	69.8 ± 19.0	66.4 ± 15.7	0.397*
Total cholesterol (mmol/L)	4.0 ± 1.2	4.7 ± 0.6	0.175*
HDL (mmol/L)	1.1 ± 0.3	1.3 ± 0.3	0.037*
Triglycerides (mmol/L)	1.4 (0.9)	1.2 (0.2)	0.742**
LDL (mmol/L)	2.2 ± 1.0	2.8 ± 0.5	0.154*
Total protein (U/L)	77.1 ± 4.9	71.4 ± 3.8	0.010*
ALT (U/L)	26.5 (55.5)	21.0 (7.0)	0.0391**
AST (U/L)	38.9 ± 18.9	25.1 ± 5.6	0.095*
ALP (U/L)	80.6 ± 12.7	76.6 ± 10.1	0.101*
GGT (U/L)	39.5 (12.5)	24.0 (9.5)	0.008**
Bilirubin (U/L)	9.5 (3.5)	13.0 (6.5)	0.175**
Albumin (U/L)	43.6 ± 2.3	40.6 ± 2.3	0.011*
PDFF (%)	12.4 ± 6.7	6.2 ± 2.8	0.013*
cT1 (ms)	823.3 ± 85.4	757.5 ± 41.6	0.039*
MRE LSM (kPa)	2.3 (0.2)	2.2 (0.3)	0.813**

Data presented as mean ± SD or median (IQR)

SD: standard deviation; IQR: interquartile range; ALT: alanine transaminase; AST: aspartate transaminase; ALP: alkaline phosphatase; GGT: gamma-glutamyl transferase; HDL: high-density lipoprotein; LDL: low-density lipoprotein; BMI: body mass index; PDFF: proton density fat fraction; cT1: iron-corrected T1; MRE: magnetic resonance elastography; LSM: liver stiffness measurement. Bolded p values indicate statistical significance (p <0.05).

^*p values obtained by paired Student’s t-test

^**p values obtained by Wilcoxon signed-rank test