Table 2.
Baseline and post-surgery serum acylcarnitine profiles (nM)
| Baseline | Post-surgery | p-value | |
|---|---|---|---|
| C2:0 | 12768.7 (12969.3) | 10032.5 (4857.2) | 0.023** |
| C3:0 | 470.9 (149.7) | 313.4 (70.1) | 0.148** |
| C4:0 | 282.8 ± 66.1 | 235.9 ± 93.4 | 0.254* |
| C5:1 | 12.6 ± 3.5 | 7.9 ± 4.9 | 0.041* |
| C5:0 | 122.8 ± 19.1 | 67.6 ± 23.0 | <0.001* |
| C4-OH | 52.9 (163.8) | 16.2 (31.4) | 0.078** |
| C6 | 72.1 ± 18.7 | 60.8 ± 13.2 | 0.042* |
| C5-OH/C3-DC | 28.1 ± 9.4 | 20.9 ± 5.5 | 0.067* |
| C4-DC,C6-OH | 48.6 ± 12.7 | 35.8 ± 7.2 | 0.019* |
| C8:1 | 176.7 ± 75.0 | 115.0 ± 61.4 | 0.091* |
| C8 | 150.7 ± 60.8 | 148.4 ± 35.6 | 0.859* |
| C5-DC | 52.5 ± 10.9 | 53.0 ± 11.8 | 0.897* |
| C8:1-OH/C6:1-DC | 36.9 ± 12.6 | 33.8 ± 7.2 | 0.595* |
| C8-OH/C6-DC | 86.1 ± 39.4 | 69.3 ± 22.0 | 0.222* |
| C10:3 | 34.9 (49.1) | 21.6 (11.6) | 0.078** |
| C10:2 | 15.0 ± 6.1 | 13.1 ± 5.9 | 0.589* |
| C10:1 | 126.6 (24.1) | 103.2 (46.3) | 0.844** |
| C10 | 241.8 ± 99.4 | 251.6 ± 54.5 | 0.698* |
| C7-DC | 20.8 ± 4.4 | 20.9 ± 5.1 | 0.630* |
| C8:1-DC | 18.3 ± 6.7 | 22.5 ± 14.6 | 0.309* |
| C8-DC | 47.0 ± 26.3 | 33.4 ± 11.1 | 0.083* |
| C12:2 | 13.2 ± 5.0 | 15.2 ± 9.5 | 0.512* |
| C12:1 | 107.2 ± 43.7 | 92.9 ± 33.3 | 0.424* |
| C12 | 90.9 ± 39.9 | 74.7 ± 20.2 | 0.169* |
| C12:2-OH/C10:2-DC | 6.7 ± 3.4 | 5.5 ± 1.9 | 0.419* |
| C12:1-OH | 14.1 (7.7) | 11.9 (5.1) | 0.742** |
| C12-OH/C10-DC | 4.8 ± 1.6 | 3.1 ± 1.2 | 0.019* |
| C14:3 | 4.9 ± 1.6 | 3.9 ± 1.8 | 0.238* |
| C14:2 | 32.1 (14.2) | 26.9 (14.0) | 0.229** |
| C14:1 | 72.3 (57.0) | 66.0 (19.5) | 0.461** |
| C14 | 34.5 ± 11.4 | 27.6 ± 9.2 | 0.203* |
| C14:3-OH/C12:3-DC | 1.2 ± 0.5 | 1.2 ± 0.6 | 0.942* |
| C14:2-OH | 5.7 ± 2.1 | 4.6 ± 2.0 | 0.096* |
| C14:1-OH | 16.5 ± 4.8 | 13.3 ± 3.7 | 0.113* |
| C14-OH/C12-DC | 12.5 ± 4.1 | 9.7 ± 3.5 | 0.247* |
| C16:3 | 7.9 ± 2.8 | 6.2 ± 2.9 | 0.082* |
| C16:2 | 8.2 (2.2) | 7.5 (1.6) | 0.313** |
| C16:1 | 26.2 (21.3) | 26.2 (7.9) | 0.250** |
| C16 | 148.3 ± 24.9 | 138.7 ± 31.7 | 0.415* |
| C16:3-OH/C14:3-DC | 1.6 ± 0.8 | 1.3 ± 0.6 | 0.340* |
| C16:2-OH | 6.8 ± 1.4 | 5.1 ± 1.5 | 0.051* |
| C16:1-OH/C14:1-DC | 7.9 (3.0) | 7.3 (1.5) | 0.313** |
| C16-OH | 13.2 ± 4.6 | 10.7 ± 2.3 | 0.098* |
| C18:3 | 8.2 ± 2.7 | 5.5 ± 1.8 | 0.001* |
| C18:2 | 96.5 ± 22.6 | 84.0 ± 21.6 | 0.048* |
| C18:1 | 181.4 ± 52.9 | 172.1 ± 26.6 | 0.643* |
| C18 | 38.9 ± 5.6 | 45.2 ± 9.3 | 0.062* |
| C18:3-OH/C16:3-DC | 4.4 ± 1.3 | 5.0 ± 2.0 | 0.524* |
| C18:2-OH/C16:2-DC | 7.0 ± 3.6 | 10.5 ± 3.9 | 0.048* |
| C18:1-OH/C16:1-DC | 9.0 ± 4.9 | 6.7 ± 2.8 | 0.165* |
| C18-OH/C16-DC | 9.0 ± 3.1 | 6.8 ± 2.2 | 0.194* |
| C20:4 | 5.6 ± 1.6 | 6.3 ± 2.7 | 0.495* |
| C20:3 | 6.0 (2.2) | 7.1 (2.3) | 0.863** |
| C20:2 | 5.5 ± 2.3 | 7.2 ± 1.3 | 0.102* |
| C20:1 | 7.6 ± 1.2 | 8.2 ± 2.2 | 0.510* |
| C20 | 4.4 ± 1.2 | 4.9 ± 1.7 | 0.340* |
| C20:3-OH/C18:3-DC | 2.5 (0.2) | 3.1 (1.6) | 0.945** |
| C20:2-OH/C18:2-DC | 2.1 ± 1.0 | 3.4 ± 1.5 | 0.118* |
| C20:1-OH/C18:1-DC | 9.0 ± 5.0 | 8.0 ± 2.7 | 0.513* |
| C20-OH/C18-DC | 8.7 ± 3.3 | 8.6 ± 2.5 | 0.970* |
| C22:5 | 2.4 ± 0.8 | 1.8 ± 0.9 | 0.223* |
| C22:4 | 1.5 ± 0.8 | 1.9 ± 1.2 | 0.316* |
| C22:3 | 0.9 ± 0.6 | 0.7 ± 0.4 | 0.529* |
| C22:2 | 0.9 (0.5) | 0.9 (0.7) | 1.000** |
| C22:1 | 2.1 ± 0.7 | 2.5 ± 0.8 | 0.410* |
| C22 | 2.7 ± 0.6 | 3.3 ± 0.9 | 0.014* |
| C24 | 21.4 ± 6.8 | 21.1 ± 7.5 | 0.947* |
| C26 | 30.5 ± 10.0 | 38.0 ± 7.4 | 0.104* |
| C28 | 2.2 ± 0.9 | 3.0 ± 0.8 | 0.187* |
Data presented as mean ± SD or median (IQR)
SD: standard deviation; IQR: interquartile range. Bolded p values indicate statistical significance (p <0.05).
*
p values obtained by paired Student’s t-test
**
p values obtained by Wilcoxon signed-rank test