Figure 2.

Changes of D_LCO, SGRQ, BSI score, and FACED score at different time points after cell treatment

(A) Left, changes of median D_LCO in both groups at week 4, 12, and 24. Data are represented as median (interquartile range, IQR). Right, boxplot showing the AUC of the D_LCO change from baseline to 24 weeks in both groups. Each dot indicated an individual patient.

(B) Left, changes of median D_LCO% of predicted in both groups at week 4, 12, and 24. Data are represented as median (IQR). Right, boxplot showing the AUC of the D_LCO% change from baseline to 24 weeks in both groups. Each dot indicated an individual patient.

(C) Column charts represent the proportion of patients who demonstrated >10% changes (improved) or < −10% changes (deteriorated) of D_LCO level at week 4, 12, and 24 after therapy.

(D) Column charts represent the proportion of patients who had >4 units changes (deteriorated) or < −4 units changes (improved) of SGRQ score at week 4, 12, and 24 after cell treatment.

(E) Violin plot showing changes in BSI score in both groups at week 4, 12, and 24.

(F) Column charts represent the proportion of patients whose BSI score improved or deteriorated for ≥1 unit at week 4, 12, and 24 after cell treatment.

(G) Violin plot showing changes in FACED score in both groups at week 4, 12, and 24.

(H) Column charts represent the proportion of patients whose FACED score improved or deteriorated ≥1 unit at week 4, 12, and 24 after cell treatment.