Figure 3.

Changes in CT damaged areas at week 24 after cell treatment

(A) The lung of patient #9003 in the control group was scanned by HRCT and 3D visualized. The red zone indicated the lung damaged area.

(B) Changes in the absolute damaged area using HRCT 3D visualization and quantification analysis in the control group. Each dot represented an individual patient. Data are represented as mean ± standard error of the mean (SEM). The paired Student’s t test was performed.

(C) The lung of patient #9018 in the cell treatment group was scanned by HRCT and 3D visualized. The red zone indicated the lung damaged area.

(D) Changes in the absolute damaged area using HRCT 3D visualization and quantification analysis in the cell treatment group. Each dot represented an individual patient. Data are represented as mean ± SEM. The paired Student’s t test was performed.

(E) Pearson correlations between the change from baseline in the damaged volume and the D_LCO in the cell treatment group. Each dot represented an individual patient.

(F) Pearson correlations between the change from baseline in the damaged volume and the D_LCO% of predicted in the cell treatment group. Each dot represented an individual patient. Reduction from baseline = −1 × (change from baseline).